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Lions vs. 49ers Week 17 MNF PPH Prediction and Preview

The NFL’s Week 17 schedule brings a Monday Night Football clash between two storied franchises with very different 2024 seasons. The Detroit Lions, eyeing the NFC’s top seed, will travel to Levi’s Stadium to face a struggling San Francisco 49ers team.

With the Lions at 13-2 and the 49ers at 6-9, this game will have major implications for Detroit’s playoff ambitions and a chance for San Francisco to salvage some pride in what has been a disappointing year. If you have ever thought about having your own PPH bookie operation, now is the time to dive in. But first, let’s dive into the predictions, odds, and trends shaping this matchup.

Lions vs. 49ers Odds and Trends

  • Spread: Lions -3.5 (-110), 49ers +3.5 (-108)
  • Moneyline: Lions -190, 49ers +166
  • Total: Over/Under 51 (-112/-108)

The Lions come into this matchup with a dominant 12-5 record against the spread (ATS) in their last 17 games and have covered four of their last five against the 49ers. Meanwhile, San Francisco has lost six of its last seven games outright and ATS, including struggling at home where they’re 4-11 ATS over their last 15 outings.

Key Players to Watch

Detroit Lions

  • Jahmyr Gibbs: With David Montgomery out, Gibbs has thrived in the Lions’ backfield, tallying 109 yards on 23 carries against Chicago. Expect him to play a pivotal role again.
  • Amon-Ra St. Brown: The Lions’ top wide receiver leads the passing attack and remains a consistent threat to opposing secondaries.

San Francisco 49ers

  • George Kittle: The Pro Bowl tight end leads the 49ers in receiving yards and touchdowns this season. His performance will be key if San Francisco hopes to compete.
  • Brock Purdy: In a contract year, Purdy has shown flashes but will face a significant challenge behind an injury-ravaged offensive line.

Game Analysis

Despite their struggles, the 49ers still have playmakers in Kittle and Deebo Samuel. However, injuries to the offensive line and backfield leave San Francisco at a disadvantage against a Lions defense ranked second in dropback EPA over the past two games. Detroit’s potent offense, led by Jared Goff, has been relentless, scoring at least 34 points in three straight games.

San Francisco’s defense, especially in the red zone, has struggled, allowing a high percentage of touchdowns inside the 20. This could lead to another big night for Detroit’s offense. On the other hand, the 49ers’ offense ranks 23rd in points per play over the last three games, making it unlikely they’ll keep pace with the high-scoring Lions.

Prediction and Pick

The Lions are motivated to secure the NFC’s top seed and exact some revenge after last year’s NFC Championship loss to San Francisco. With their high-powered offense and superior depth, Detroit should dominate a depleted 49ers roster. Expect the Lions to win by at least a touchdown.

Spread Lean: Lions -3.5 (-110)

While Detroit is capable of scoring in bunches, their defensive injuries may slow the game’s tempo. The 49ers, with limited weapons and a shaky offensive line, are unlikely to contribute much to the scoreboard. This game could see the Lions build a lead and grind out the clock in the second half.

Over/Under Lean: Under 50.5 (-110)

Conclusion

This should be a great game on Monday Night Football. Be sure to checkout more of what WagerHome has to offer here, and get started with one of the best PPH bookies around as we head into the playoff season.

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