Week 7 of the NFL season brings 15 games and plenty of betting value. The schedule starts Thursday in Cincinnati and wraps up Monday with a doubleheader. With teams starting to separate in the standings, every matchup matters. Bettors can find fresh lines, live player props, and manage action directly through WagerHome.com.
The Bills and Ravens are off this week, but the slate still offers strong favorites, tight spreads, and a few good underdog plays. Here’s a look at all the matchups, odds, and PPH predictions for Week 7.
Thursday, Oct 16
Pittsburgh Steelers (-5.5) at Cincinnati Bengals | Total 43.5
Pittsburgh enters 4-1 behind Aaron Rodgers and a defense ranked top five in takeaways. The Bengals are banged up, with Joe Flacco expected to start at quarterback. Cincinnati has lost four of its last five games and may again struggle to protect the pocket.
The Steelers just limited the Browns to nine points and should control the line of scrimmage. Expect a conservative game plan from both sides, with Pittsburgh doing enough on defense to cover.
Pick: Steelers –5.5 (24-17)
Sunday, Oct 19 – London Game
Los Angeles Rams (-3) vs Jacksonville Jaguars | Total 44.5
This is the third straight year the Jaguars have played in London, but this time they’re the away team. The Rams have been sharp offensively behind a balanced pass game led by Matthew Stafford. Jacksonville has struggled to stop big plays through the air.
The Rams arrived early in the week to adjust to the time change, which usually helps performance. If Stafford avoids turnovers, Los Angeles should handle the neutral-site crowd.
Pick: Rams –3 (27-20)
Sunday Early Window
New Orleans Saints at Chicago Bears (-4.5) | Total 46.5
Chicago has turned its season around with improved quarterback play and a more balanced attack. The Bears have scored 27 or more in three straight home games. The Saints continue to rely on defense while ranking near the bottom in scoring offense.
In windy conditions at Soldier Field, the Bears’ ground game should control tempo. Expect a low-scoring start but a comfortable Chicago win.
Pick: Bears –4.5 (26-17)
Miami Dolphins at Cleveland Browns (-2.5) | Total 40.5
The Dolphins’ offense has cooled after a hot start, and now they meet the NFL’s best defense in Cleveland. The Browns allow the fewest yards per game and thrive at home. Weather could be a factor in this one, favoring the defensive side.
If Cleveland limits Tyreek Hill’s deep routes, Miami could struggle to sustain drives. The Browns’ run-heavy approach and home edge make them the safer side.
Pick: Browns –2.5 (20-16)
Las Vegas Raiders at Kansas City Chiefs (-11.5) | Total 45.5
The Chiefs have dropped two straight but remain dangerous at Arrowhead. Patrick Mahomes faces a Raiders defense that has allowed over 250 passing yards per game. Las Vegas continues to rotate quarterbacks and ranks bottom five in scoring.
Kansas City’s offense should bounce back in a big way here. Expect Travis Kelce and Rashee Rice to find space against the Raiders’ zone coverage.
Pick: Chiefs –11.5 (31-17)
Philadelphia Eagles (-2.5) at Minnesota Vikings | Total 43.5
Both teams enter under pressure after recent losses. Philadelphia’s secondary has struggled, while Minnesota is coming off a bye and gets a healthy offense back. The Vikings have won five straight home games decided by a field goal or less.
This feels like a coin-flip matchup, but momentum favors the home side. Kirk Cousins should find success on play-action, and the Vikings can steal this one late.
Pick: Vikings +2.5 (23-21)
Carolina Panthers (-1.5) at New York Jets | Total 42.5
Carolina’s young offense has shown flashes, and the defense has improved against the run. The Jets continue to deal with offensive inconsistency and injuries up front. Both teams rely heavily on field position and turnovers.
Expect a defensive game with limited scoring opportunities. Carolina’s run game gives them a small edge on the road.
Pick: Panthers –1.5 (20-17)
New England Patriots (-7) at Tennessee Titans | Total 41.5
The Patriots’ defense continues to carry them, ranking top three in takeaways. Tennessee has struggled to score and ranks last in red-zone efficiency. Bill Belichick’s team should control clock and tempo from start to finish.
The Titans’ inability to protect their quarterback makes this matchup difficult. Expect a methodical but comfortable win for New England.
Pick: Patriots –7 (24-13)
Sunday Late Window
New York Giants at Denver Broncos (-7) | Total 40.5
The Giants’ offense ranks near the bottom in nearly every category. Denver has shown better play at home, winning three straight in Mile High. The Broncos defense has improved against the run, which will be key here.
If Russell Wilson avoids mistakes, Denver should win comfortably. The Giants’ offensive struggles continue.
Pick: Broncos –7 (23-10)
Indianapolis Colts at Los Angeles Chargers (-1.5) | Total 48.5
This could be the most entertaining game of the week. Both teams play fast and lean on strong quarterback play. The Colts’ defense has given up big passing plays, and that fits well for Justin Herbert and the Chargers.
Expect points on both sides, but Los Angeles’ home-field advantage and late-game execution should make the difference.
Pick: Chargers –1.5 (28-27)
Green Bay Packers (-6.5) at Arizona Cardinals | Total 44.5
Green Bay is starting to find balance with the run game leading the way. Arizona remains one of the youngest rosters in football and struggles to close games. Lambeau’s offense should have no problem on the road.
Look for the Packers to get up early and rely on their defense to close. Arizona may find a few late scores but not enough to threaten the spread.
Pick: Packers –6.5 (27-14)
Washington Commanders at Dallas Cowboys (-2.5) | Total 54.5
Dallas returns home after a road loss and needs a response. Washington’s offense has been strong, but the defense gives up explosive plays. Dak Prescott has thrown six touchdowns in his last two home games.
Expect a fast start and plenty of scoring from both sides. Dallas’ pass rush could be the difference late.
Pick: Cowboys –2.5 (30-27)
Sunday Night Football
Atlanta Falcons at San Francisco 49ers (-2.5) | Total 47.5
San Francisco comes off a bye week and should be fresh. The 49ers’ defense ranks top five in sacks, which will test Atlanta’s offensive line. The Falcons are inconsistent on the road and lean too heavily on the run.
With rest and crowd behind them, San Francisco should control the game. Expect a steady effort from Brock Purdy and a defense-led win.
Pick: 49ers –2.5 (27-20)
Monday Night Football Doubleheader
Tampa Bay Buccaneers at Detroit Lions (-5.5) | Total 52.5
The Lions have been a top-scoring team at home, averaging 30 points per game. Tampa Bay’s secondary has struggled against high-volume passing attacks. Jared Goff should find success with Amon-Ra St. Brown in space.
Detroit’s ground game gives them more balance. Expect a high-scoring contest indoors but Detroit to cover late.
Pick: Lions –5.5 (31-24)
Houston Texans at Seattle Seahawks (-3) | Total 41.5
Seattle is tough to beat at home, winning 11 of its last 13 night games. Houston continues to show progress but will face one of the loudest stadiums in football. Crowd noise could limit their communication up front.
The Seahawks’ defense has quietly improved, and Geno Smith should be efficient. Expect a lower total but a solid home win.
Pick: Seahawks –3 (23-17)
Byes
Baltimore Ravens, Buffalo Bills
Closing Thoughts
Week 7 has a mix of large favorites and tight lines, giving bettors several angles to attack. The Chiefs and Packers look like safe plays, while the Vikings and Browns offer strong value as small underdogs. As always, shop for the best number and stay updated through WagerHome.com to manage action, set lines, and access live PPH tools throughout the NFL season.
