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2025 ACC Football PPH Prediction & Picks – Full Season Betting Preview

The 2025 ACC football season kicks off on August 23, and sportsbooks have already set the odds for who will win the conference. Clemson is the favorite at +240, with Miami, Louisville, and SMU close behind. The conference now includes 18 teams, and with no divisions, the top two will meet in Charlotte for the ACC Championship on December 6.

Clemson looks for a repeat title after beating SMU 34-31 in last year’s championship game. But the path to the playoff is crowded. Miami added Georgia transfer Carson Beck, Louisville brought in USC QB Miller Moss, and SMU returns top dual-threat QB Kevin Jennings. For bettors, now’s the time to lock in futures or become a PPH bookie with WagerHome. Get started today at WagerHome.com.

Clemson Tigers Preview – Most Complete Team in the Country?

Clemson is the preseason favorite at +240 and returns 77.9% of its production, the highest in the FBS. Cade Klubnik enters his junior year with All-American WR Antonio Williams and a veteran offensive line. The Tigers lost Phil Mafah and TE Jake Briningstool but should reload quickly.

On defense, they return eight starters from a unit that led the league in disruption. The new coordinator Tom Allen, formerly at Penn State, takes over the playcalling. Clemson avoids Miami in the regular season and gets SMU at home.

Win Total: 9.5 (Over -200)
Prediction: 10-2 overall, ACC Championship Game berth

Miami Hurricanes Preview – Transfer QB Sparks Playoff Hopes

Miami is +280 to win the ACC after finishing 10-3 last season. Carson Beck transfers in from Georgia and gives the Canes a proven passer with playoff experience. The Hurricanes return seven starters on offense and eight on defense, including edge rusher Rueben Bain.

The offensive line is strong, and RB Mark Fletcher Jr. will be a key contributor. If Beck stays healthy and cuts down on mistakes, Miami could be back in the ACC title game for the first time since 2017.

Win Total: 9.5 (Under -160 / Over +135)
Prediction: 10-2 overall, strong ACC contender

Louisville Cardinals Preview – Tough Schedule, Veteran QB

Louisville is +500 and returns seven starters on offense and six on defense. Miller Moss comes in from USC and has an elite O-line in front of him. WR Chris Bell and RB Isaac Brown lead a solid group of playmakers.

The defense ranked 22nd in SP+ last year and brings back key starters like TJ Quinn and Stanquan Clark. But games against Clemson, SMU, Miami, and Kentucky make for a tough road.

Win Total: 8.5 (Over -130)
Prediction: 8-4 overall, top-5 ACC finish

SMU Mustangs Preview – Year 2 in ACC After Title Game Loss

SMU is listed between +500 and +900 to win the ACC. QB Kevin Jennings is back after a strong 2024 season, though he must cut down on turnovers. The offense ranked 10th in SP+ and should remain explosive.

The defense brings back just five starters but had 43 sacks last season. SMU avoids Florida State and NC State in conference play but travels to Clemson.

Win Total: 8.5
Prediction: 9-3 overall, possible ACC Championship return

Georgia Tech Yellow Jackets Preview – Veteran QB Leads the Way

Georgia Tech is +1600 and has the second-most experience in the ACC. QB Haynes King returns with dual-threat ability and strong production from 2024. RB Jamal Haynes and WR Malik Rutherford help round out the offense.

The defense was ranked 75th in SP+ last year and needs to improve on third downs and havoc rate. They avoid both Clemson and SMU, giving them a favorable schedule.

Win Total: 7.5 (Over -150)
Prediction: 8-4 overall, sneaky top-4 ACC finisher

Florida State Seminoles Preview – Coaching Overhaul After Collapse

Florida State is +1800 after a disappointing 2024. Gus Malzahn takes over as offensive coordinator, and Tony White leads the defense. They added talent in the portal but lost multiple starters on both sides.

A projected record of 7-5 seems fair given a middle-of-the-pack schedule and the time needed for new schemes to take hold.

Win Total: 6.5
Prediction: 7-5 overall, outside CFP mix

North Carolina Tar Heels Preview – Belichick Era Begins

UNC is +2000 in Bill Belichick’s first year as head coach. Expectations are high, but transitions like this usually take time. The defense must improve, and the offense needs a new identity post-Drake Maye.

They have a balanced schedule but face Clemson and Georgia Tech.

Win Total: 7.5
Prediction: 7-5 overall, middle of the pack

Other ACC Teams Outlook

NC State (+6000): QB CJ Bailey returns after a strong freshman year. The Wolfpack should finish around .500.
Duke (+3500): New QB Darian Mensah leads a rising program under Manny Diaz. 8-4 is realistic.
Virginia Tech (+4000): Veteran QB Kyron Drones leads a decent roster. Soft schedule helps.
Pitt (+9000): RB Desmond Reid leads the offense. A bowl game is the ceiling.
Syracuse (+6500): LSU transfer Rickie Collins gets the start at QB. In rebuild mode.
Boston College (+15000): Bill O’Brien brings NFL experience but depth is thin.
Virginia (+15000): Closed 2024 on a three-game losing streak. More of the same likely.
California (+8500): Jaydn Ott is the centerpiece but QB situation is unclear.
Wake Forest (+35000): Massive roster turnover. Likely a 4-win team.
Stanford (+40000): No bowl games since 2018. Expect another rough season.

PPH Betting Prediction

Clemson at +240 is still the best bet. The Tigers return the most production, have the most consistent coaching, and don’t play Miami in the regular season. Miami at +280 is a close second but faces more pressure with a new quarterback.

If you’re a bettor or looking to run your own book this football season, now is the time to join WagerHome.com. Track your players, manage lines, and control your sportsbook all in one place with our top-rated PPH software.

PPH Betting Pick: Clemson to win the ACC (+240)

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